Ocular Oncology Case Reports in Ocular Oncology

46 RETINA TODAY SEPTEMBER 2015 M etastatic tumors in the eye are most commonly found in the choroid.1 In an analysis of 950 metastatic foci in 520 eyes, the tumors were located in the choroid in 88% of cases.1 This is believed to be due to the abundant vascular supply to the choroid from the posterior ciliary arteries.2 In this analysis, the most common sites of primary cancer to metastasize to the eye included carcinomas of the breast (47%) and lung (21%), while metastasis from the kidney was not often found (2%).1 The clinical features of choroidal metastases include one or more yellow lesions, generally in the macula or paramacular region, about 3 mm in thickness and 6 mm in base, ranging from tiny to large tumors depending on the stage of discovery.3 Associated features of subretinal fluid and overlying retinal pigment epithelium mottling are typical.1 Metastasis from renal cell carcinoma (RCC) to the eye can appear different compared with others, as this tumor displays more of an orange color, occasionally with subretinal hemorrhage or exudation.3 Metastases from RCC also tend to be thicker than metastases from other cancers, with mean thickness of 4 mm.1